Journal
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Volume 9, Issue 1, Pages 33-46Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrm2310
Keywords
-
Categories
Ask authors/readers for more resources
Segregation of the replicated genome during cell division in eukaryotes requires the kinetochore to link centromeric DNA to spindle microtubules. The kinetochore is composed of a number of conserved protein complexes that direct its specification and assembly, bind to spindle microtubules and regulate chromosome segregation. Recent studies have identified more than 80 kinetochore components, and are revealing how these proteins are organized into the higher order kinetochore structure, as well as how they function to achieve proper chromosome segregation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available