Journal
NATURE REVIEWS MICROBIOLOGY
Volume 11, Issue 4, Pages 277-284Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrmicro2989
Keywords
-
Categories
Funding
- Swiss National Science foundation (SNF)
- German Research Foundation (DFG)
- German Federal Ministry of Education and Research (BMBF)
Ask authors/readers for more resources
Hundreds of bacterial species make up the mammalian intestinal microbiota. Following perturbations by antibiotics, diet, immune deficiency or infection, this ecosystem can shift to a state of dysbiosis. This can involve overgrowth (blooming) of otherwise under-represented or potentially harmful bacteria (for example, pathobionts). Here, we present evidence suggesting that dysbiosis fuels horizontal gene transfer between members of this ecosystem, facilitating the transfer of virulence and antibiotic resistance genes and thereby promoting pathogen evolution.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available