Journal
NATURE REVIEWS MICROBIOLOGY
Volume 6, Issue 1, Pages 11-16Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrmicro1814
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When Shigella infect the intestinal epithelium, they deliver several effectors through the type III secretion system (T3SS) into the surrounding space and directly into the host-cell. cytoplasm, where they can mimic and usurp host cellular functions or subvert host-cell signalling pathways and the immune response. Although bacterial strategies and mechanisms of infection vary greatly, recent studies of Shigella effectors have revealed that Shigella possess a highly evolved strategy for infection.
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