Journal
NATURE REVIEWS MICROBIOLOGY
Volume 6, Issue 1, Pages 53-66Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrmicro1788
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Funding
- NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [R01AI030479, R01AI048683, U54AI057141] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF DENTAL &CRANIOFACIAL RESEARCH [T32DE007132] Funding Source: NIH RePORTER
- NIAID NIH HHS [R01 AI30479, U54 AI057141, R01 AI048683] Funding Source: Medline
- NIDCR NIH HHS [T32 DE07132] Funding Source: Medline
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Salmonellae are important causes of enteric diseases in all vertebrates. Characterization of the molecular mechanisms that underpin the interactions of salmonellae with their animal hosts has advanced greatly over the past decade, mainly through the study of Salmonella enterica serovar Typhimurium in tissue culture and animal models of infection. Knowledge of these bacterial processes and host responses has painted a dynamic and complex picture of the interaction between salmonellae and animal cells. This Review focuses on the molecular mechanisms of these host-pathogen interactions, in terms of their context, significance and future perspectives.
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