Journal
NATURE REVIEWS GENETICS
Volume 15, Issue 5, Pages 347-359Publisher
NATURE PORTFOLIO
DOI: 10.1038/nrg3707
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Funding
- US National Institutes of Health [U54-HG006484, R24-OD011173]
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Advances in genome sequencing technologies have created new opportunities for comparative primate genomics. Genome assemblies have been published for various primate species, and analyses of several others are underway. Whole-genome assemblies for the great apes provide remarkable new information about the evolutionary origins of the human genome and the processes involved. Genomic data for macaques and other non-human primates offer valuable insights into genetic similarities and differences among species that are used as models for disease-related research. This Review summarizes current knowledge regarding primate genome content and dynamics, and proposes a series of goals for the near future.
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