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The evolutionary causes and consequences of sex-biased gene expression

Journal

NATURE REVIEWS GENETICS
Volume 14, Issue 2, Pages 83-87

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/nrg3376

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Funding

  1. Deutsche Forschungsgemeinschaft
  2. European Research Council
  3. Knut and Alice Wallenberg Foundation
  4. Swedish Research Council

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Females and males often differ extensively in their physical traits. This sexual dimorphism is largely caused by differences in gene expression. Recent advances in genomics, such as RNA sequencing (RNA-seq), have revealed the nature and extent of sex-biased gene expression in diverse species. Here we highlight new findings regarding the causes of sex-biased expression, including sexual antagonism and incomplete dosage compensation. We also discuss how sex-biased expression can accelerate the evolution of sex-linked genes.

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