Journal
NATURE REVIEWS GENETICS
Volume 14, Issue 3, Pages 179-190Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrg3395
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Funding
- Academy of Finland [250435, 252597, 259944]
- Finnish Cultural Foundation
- Landesoffensive zur Entwicklung wissenschaftlich-okonomischer Exzellenz (LOEWE) of the state Hesse in Germany through the Biodiversity and Climate Research Centre (Bik-F) in Frankfurt am Main
- Academy of Finland (AKA) [252597, 250435, 259944, 250435, 252597, 259944] Funding Source: Academy of Finland (AKA)
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Comparative studies of the divergence of quantitative traits and neutral molecular markers, known as Q(ST)-F-ST comparisons, provide a means for researchers to distinguish between natural selection and genetic drift as causes of population differentiation in complex polygenic traits. The use of Q(ST)-F-ST comparisons has increased rapidly in the last few years, highlighting the utility of this approach for addressing a wide range of questions that are relevant to evolutionary and ecological genetics. These studies have also provided lessons for the design of future Q(ST)-F-ST comparisons. Methods based on the Q(ST)-F-ST approach could also be used to analyse various types of 'omics' data in new and revealing ways.
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