Journal
NATURE REVIEWS GENETICS
Volume 13, Issue 6, Pages 421-428Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrg3239
Keywords
-
Categories
Ask authors/readers for more resources
Although random monoallelic expression has been known for decades to affect genes on the X chromosome in female placental mammals, until a few years ago it was thought that there were few autosomal genes that were regulated in this manner. New tools for assaying gene expression genome-wide are now revealing that there are perhaps more genes that are subject to random monoallelic expression on mammalian autosomes than there are on the X chromosome and that these expression properties are achieved by diverse molecular mechanisms. This mode of expression has the potential to have an impact on natural selection and on the evolution of gene families.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available