Journal
NATURE REVIEWS ENDOCRINOLOGY
Volume 8, Issue 9, Pages 515-516Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrendo.2012.125
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Whether treatment of hyperglycaemia prevents progression of diabetic nephropathy is controversial. Intensive glycaemic control reduces the risk of microalbuminuria and macroalbuminuria, but there is no clear-cut evidence showing that it reduces doubling of serum creatinine levels or risk of death from kidney disease. Larger studies or further follow-up of previous trials are required to better assess renal outcomes.
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