4.6 Review

The role of interleukins in insulin resistance and type 2 diabetes mellitus

Related references

Note: Only part of the references are listed.
Article Endocrinology & Metabolism

Gender-based dimorphic pattern for interleukin-1 receptor antagonist in type 2 diabetes mellitus

J. Ybarra et al.

DIABETES & METABOLISM (2008)

Article Endocrinology & Metabolism

Interleukin-18 resistance in patients with obesity and type 2 diabetes mellitus

G. R. C. Zilverschoon et al.

INTERNATIONAL JOURNAL OF OBESITY (2008)

Article Multidisciplinary Sciences

Interleukin-6 regulates pancreatic α-cell mass expansion

Helga Ellingsgaard et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Biochemistry & Molecular Biology

Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway

Jeong-Ho Kim et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Endocrinology & Metabolism

Interleukin-18 in plasma and adipose tissue: effects of obesity, insulin resistance, and weight loss

Jens M. Bruun et al.

EUROPEAN JOURNAL OF ENDOCRINOLOGY (2007)

Article Endocrinology & Metabolism

Increased number of islet-associated macrophages in type 2 diabetes

Jan A. Ehses et al.

DIABETES (2007)

Article Endocrinology & Metabolism

Interleukin-6 directly increases glucose metabolism in resting human skeletal muscle

Stephan Glund et al.

DIABETES (2007)

Article Endocrinology & Metabolism

IL-6 increases muscle insulin sensitivity only at superphysiological levels

Paige C. Geiger et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)

Article Biochemistry & Molecular Biology

Hepatic overexpression of glycerol-sn-3-phosphate acyltransferase 1 in rats causes insulin resistance

Cynthia A. Nagle et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Medicine, General & Internal

Interleukin-1-receptor antagonist in type 2 diabetes mellitus

Claus M. Larsen et al.

NEW ENGLAND JOURNAL OF MEDICINE (2007)

Review Physiology

Disordered lipid metabolism and the pathogenesis of insulin resistance

David B. Savage et al.

PHYSIOLOGICAL REVIEWS (2007)

Article Multidisciplinary Sciences

Inflammation and metabolic disorders

Goekhan S. Hotamisligil

NATURE (2006)

Article Endocrinology & Metabolism

Signaling specificity of interleukin-6 action on glucose and lipid metabolism in skeletal muscle

Lubna Al-Khalili et al.

MOLECULAR ENDOCRINOLOGY (2006)

Article Endocrinology & Metabolism

Interleukin-1 system gene polymorphisms are associated with fat mass in young men

Louise Strandberg et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2006)

Article Biochemistry & Molecular Biology

Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance

MG Netea et al.

NATURE MEDICINE (2006)

Article Biochemistry & Molecular Biology

Direct cross-talk of interleukin-6 and insulin signal transduction via insulin receptor substrate-1 in skeletal muscle cells

C Weigert et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Endocrinology & Metabolism

Interleukin-6 acts as insulin sensitizer on glycogen synthesis in human skeletal muscle cells by phosphorylation of Ser473 of Akt

C Weigert et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2005)

Article Endocrinology & Metabolism

Interleukin-6 depletion selectively improves hepatic insulin action in obesity

PJ Klover et al.

ENDOCRINOLOGY (2005)

Article Biochemistry & Molecular Biology

Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs

LE Hammond et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB

DS Cai et al.

NATURE MEDICINE (2005)

Article Endocrinology & Metabolism

Acute IL-6 treatment increases fatty acid turnover in elderly humans in vivo and in tissue culture in vitro

EW Petersen et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2005)

Article Medicine, Research & Experimental

PKC-θ knockout mice are protected from fat-induced insulin resistance

JK Kim et al.

JOURNAL OF CLINICAL INVESTIGATION (2004)

Article Endocrinology & Metabolism

Higher production of IL-8 in visceral vs. subcutaneous adipose tissue. Implication of nonadipose cells in adipose tissue

JM Bruun et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2004)

Article Endocrinology & Metabolism

Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: absence of development of age-related obesity

GB Di Gregorio et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2004)

Article Endocrinology & Metabolism

Interleukin-6 regulates human adipose tissue lipid metabolism and leptin production in vitro

ME Trujillo et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)

Article Endocrinology & Metabolism

Regulatory effects of interleukin (IL)-1, interferon-β, and IL-4 on the production of IL-1 receptor antagonist by human adipose tissue

CE Juge-Aubry et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)

Article Multidisciplinary Sciences

Leptin modulates β cell expression of IL-1 receptor antagonist and release of IL-lβ in human islets

K Maedler et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

Chronic interleukin-6 (IL-6) treatment increased IL-6 secretion and induced insulin resistance in adipocyte: prevention by rosiglitazone

C Lagathu et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)

Review Biochemistry & Molecular Biology

Principles of interleukin (IL)-6-type cytokine signalling and its regulation

PC Heinrich et al.

BIOCHEMICAL JOURNAL (2003)

Article Endocrinology & Metabolism

Interleukin-6 stimulates lipolysis and fat oxidation in humans

G van Hall et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2003)

Article Endocrinology & Metabolism

Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice

PJ Klover et al.

DIABETES (2003)

Article Endocrinology & Metabolism

Interleukin-6 induces cellular insulin resistance in hepatocytes

JJ Senn et al.

DIABETES (2002)

Article Medicine, Research & Experimental

Glucose-induced β cell production of IL-1β contributes to glucotoxicity in human pancreatic islets

K Maedler et al.

JOURNAL OF CLINICAL INVESTIGATION (2002)

Article Cell Biology

Immunomodulatory actions of leptin

CE Juge-Aubry et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2002)

Article Neurosciences

Metabolic effects of interleukin-6 in human splanchnic and adipose tissue

D Lyngso et al.

JOURNAL OF PHYSIOLOGY-LONDON (2002)

Article Biochemistry & Molecular Biology

Leptin induces IL-1 receptor antagonist expression in the brain

T Hosoi et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)

Article Biochemistry & Molecular Biology

Interleukin-6-deficient mice develop mature-onset obesity

V Wallenius et al.

NATURE MEDICINE (2002)

Review Multidisciplinary Sciences

Global and societal implications of the diabetes epidemic

P Zimmet et al.

NATURE (2001)

Article Critical Care Medicine

Proinflammatory cytokines

CA Dinarello

CHEST (2000)

Article Immunology

Arterial inflammation in mice lacking the interleukin 1 receptor antagonist gene

MJH Nicklin et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2000)