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Vardenafil, but not sildenafil or tadalafil, has calcium-channel blocking activity in rabbit isolated pulmonary artery and human washed platelets
H. A. Toque et al.
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Spectrin-anchored phosphodiesterase 4D4 restricts cAMP from disrupting microtubules and inducing endothelial cell gap formation
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Mutation in PDE8B, a cyclic AMP-specific phosphodiesterase in adrenal hyperplasia
Anelia Horvath et al.
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Lindsay S. Wilson et al.
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S. Hossein Fatemi et al.
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Functional Rescue of Degenerating Photoreceptors in Mice Homozygous for a Hypomorphic cGMP Phosphodiesterase 6 b Allele ( Pde6bH620Q)
Richard J. Davis et al.
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Conformational variations of both phosphodiesterase-5 and inhibitors provide the structural basis for the physiological effects of vardenafil and sildenafil
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James Surapisitchat et al.
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PI3Kγ is required for PDE4, not PDE3, activity in subcellular Microdomains containing the sarcoplasmic reticular calcium ATPase in cardiomyocytes
Benoit-Gilles Kerfant et al.
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p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway
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Faiyaz Ahmad et al.
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Behavioral phenotypes of Disc1 missense mutations in mice
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Protein kinase A phosphorylation of human phosphodiesterase 3B promotes 14-3-3 protein binding and inhibits phosphatase-catalyzed inactivation
Daniel Palmer et al.
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Inflammation and metabolic disorders
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Phosphodiesterase genes are associated with susceptibility to major depression and antidepressant treatment response
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Enantiomer discrimination illustrated by the high resolution crystal structures of type 4 phosphodiesterase
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Phosphodiesterase inhibitors in airways disease
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AKAP3 selectively binds PDE4A isoforms in bovine spermatozoa
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Sildenafil citrate therapy for pulmonary arterial hypertension
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The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways
KL Dodge-Kafka et al.
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Specific role of phosphodiesterase 4B in lipopolysaccharide-induced signaling in mouse macrophages
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3′,5′-Cyclic nucleotide phosphodiesterase 11A:: localization in human tissues
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Per-Arnt-Sim domain-dependent association of cAMP-phosphodiesterase 8A1 with IκB proteins
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Nonredundant function of phosphodiesterases 4D and 4B in neutrophil recruitment to the site of inflammation
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A glutamine switch mechanism for nucleotide selectivity by phosphodiesterases
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Phosphodiesterase 7A-deficient mice have functional T cells
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GB Bolger et al.
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AWD 12-281 a highly selective phosphodiesterase 4 inhibitor, is effective in the prevention and treatment of inflammatory reactions in a model of allergic dermatitis
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β-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates β-adrenoceptor switching from Gs to Gi
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