4.6 Editorial Material

TARGETED THERAPIES Sunitinib versus interferon-alpha in metastatic RCC

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NATURE REVIEWS CLINICAL ONCOLOGY
Volume 7, Issue 1, Pages 7-8

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NATURE PUBLISHING GROUP
DOI: 10.1038/nrclinonc.2009.173

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Motzer and colleagues present updated results from a multicenter, phase III trial of sunitinib versus interferon-alpha as first-line treatment for patients with metastatic renal-cell carcinoma. The observed improvement in overall survival for patients treated with sunitinib further establishes this agent as the reference standard for first-line treatment of good-risk and intermediate-risk patients with metastatic renal cancer.

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