Journal
NATURE NEUROSCIENCE
Volume 17, Issue 9, Pages 1138-1140Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nn.3792
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Funding
- NIA NIH HHS [RF1 AG044546, RF1 AG053303, R01 AG044546] Funding Source: Medline
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Two independent epigenome-wide association studies of Alzheimer's disease cohorts have identified overlapping methylation signals in four loci, ANK1, RPL13, RHBDF2 and CDH23, not previously associated with Alzheimer's disease. These studies also suggest that epigenetic changes contribute more to Alzheimer's disease than expected.
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