Journal
NATURE NEUROSCIENCE
Volume 16, Issue 3, Pages 264-266Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nn.3329
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Funding
- US National Science Foundation
- Simons Foundation
- Machiah Foundation
- Paul G. Allen Family Foundation
- US National Institutes of Health [DP1OD003560, R21AG038771, R21MH099469]
- Div Of Biological Infrastructure
- Direct For Biological Sciences [1063292] Funding Source: National Science Foundation
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Using Ca2+ imaging in freely behaving mice that repeatedly explored a familiar environment, we tracked thousands of CA1 pyramidal cells' place fields over weeks. Place coding was dynamic, as each day the ensemble representation of this environment involved a unique subset of cells. However, cells in the similar to 15-25% overlap between any two of these subsets retained the same place fields, which sufficed to preserve an accurate spatial representation across weeks.
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