Related references
Note: Only part of the references are listed.Exaggerated translation causes synaptic and behavioural aberrations associated with autism
Emanuela Santini et al.
NATURE (2013)
Lovastatin Corrects Excess Protein Synthesis and Prevents Epileptogenesis in a Mouse Model of Fragile X Syndrome
Emily K. Osterweil et al.
NEURON (2013)
The Pathophysiology of Fragile X (and What It Teaches Us about Synapses)
Asha L. Bhakar et al.
ANNUAL REVIEW OF NEUROSCIENCE, VOL 35 (2012)
Molecular Mechanisms of Fragile X Syndrome: A Twenty-Year Perspective
Michael R. Santoro et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 7 (2012)
Pharmacological treatment of fragile X syndrome with GABAergic drugs in a knockout mouse model
Inge Heulens et al.
BEHAVIOURAL BRAIN RESEARCH (2012)
Genetic manipulation of STEP reverses behavioral abnormalities in a fragile X syndrome mouse model
S. M. Goebel-Goody et al.
GENES BRAIN AND BEHAVIOR (2012)
Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome
C. A. Hoeffer et al.
GENES BRAIN AND BEHAVIOR (2012)
Inhibition of GSK3β improves hippocampus-dependent learning and rescues neurogenesis in a mouse model of fragile X syndrome
Weixiang Guo et al.
HUMAN MOLECULAR GENETICS (2012)
Altered maturation of the primary somatosensory cortex in a mouse model of fragile X syndrome
Sally M. Till et al.
HUMAN MOLECULAR GENETICS (2012)
Excess Protein Synthesis in FXS Patient Lymphoblastoid Cells Can Be Rescued with a p110β-Selective Inhibitor
Christina Gross et al.
MOLECULAR MEDICINE (2012)
Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome
Jennifer A. Ronesi et al.
NATURE NEUROSCIENCE (2012)
Genetic Removal of p70 S6 Kinase 1 Corrects Molecular, Synaptic, and Behavioral Phenotypes in Fragile X Syndrome Mice
Aditi Bhattacharya et al.
NEURON (2012)
Chronic Pharmacological mGlu5 Inhibition Corrects Fragile X in Adult Mice
Aubin Michalon et al.
NEURON (2012)
Reversal of Disease-Related Pathologies in the Fragile X Mouse Model by Selective Activation of GABAB Receptors with Arbaclofen
Christina Henderson et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Effects of STX209 (Arbaclofen) on Neurobehavioral Function in Children and Adults with Fragile X Syndrome: A Randomized, Controlled, Phase 2 Trial
Elizabeth M. Berry-Kravis et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Cytoplasmic RNA-Binding Proteins and the Control of Complex Brain Function
Jennifer C. Darnell et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
Differences in AMPA and Kainate Receptor Interactomes Facilitate Identification of AMPA Receptor Auxiliary Subunit GSG1L
Natalie F. Shanks et al.
CELL REPORTS (2012)
FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism
Jennifer C. Darnell et al.
CELL (2011)
Neural circuit architecture defects in a Drosophila model of Fragile X syndrome are alleviated by minocycline treatment and genetic removal of matrix metalloproteinase
Saul S. Siller et al.
DISEASE MODELS & MECHANISMS (2011)
Abnormal Presynaptic Short-Term Plasticity and Information Processing in a Mouse Model of Fragile X Syndrome
Pan-Yue Deng et al.
JOURNAL OF NEUROSCIENCE (2011)
Mutations causing syndromic autism define an axis of synaptic pathophysiology
Benjamin D. Auerbach et al.
NATURE (2011)
Bidirectional Regulation of Dendritic Voltage-Gated Potassium Channels by the Fragile X Mental Retardation Protein
Hye Young Lee et al.
NEURON (2011)
Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome
Dilja D. Krueger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Open-label add-on treatment trial of minocycline in fragile X syndrome
Carlo Paribello et al.
BMC NEUROLOGY (2010)
Excess Phosphoinositide 3-Kinase Subunit Synthesis and Activity as a Novel Therapeutic Target in Fragile X Syndrome
Christina Gross et al.
JOURNAL OF NEUROSCIENCE (2010)
Dysregulation of mTOR Signaling in Fragile X Syndrome
Ali Sharma et al.
JOURNAL OF NEUROSCIENCE (2010)
Hypersensitivity to mGluR5 and ERK1/2 Leads to Excessive Protein Synthesis in the Hippocampus of a Mouse Model of Fragile X Syndrome
Emily K. Osterweil et al.
JOURNAL OF NEUROSCIENCE (2010)
Fragile X Mental Retardation Protein Is Required for Rapid Experience-Dependent Regulation of the Potassium Channel Kv3.1b
John G. Strumbos et al.
JOURNAL OF NEUROSCIENCE (2010)
Delayed Stabilization of Dendritic Spines in Fragile X Mice
Alberto Cruz-Martin et al.
JOURNAL OF NEUROSCIENCE (2010)
Functional impact of global rare copy number variation in autism spectrum disorders
Dalila Pinto et al.
NATURE (2010)
Critical Period Plasticity Is Disrupted in the Barrel Cortex of Fmr1 Knockout Mice
Emily G. Harlow et al.
NEURON (2010)
Early developmental alterations in GABAergic protein expression in fragile X knockout mice
Daniel C. Adusei et al.
NEUROPHARMACOLOGY (2010)
GSK3 Influences Social Preference and Anxiety-Related Behaviors during Social Interaction in a Mouse Model of Fragile X Syndrome and Autism
Marjelo A. Mines et al.
PLOS ONE (2010)
Dendritic spine instability and insensitivity to modulation by sensory experience in a mouse model of fragile X syndrome
Feng Pan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Characterization and reversal of synaptic defects in the amygdala in a mouse model of fragile X syndrome
Aparna Suvrathan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
mTOR signaling: At the crossroads of plasticity, memory and disease
Charles A. Hoeffer et al.
TRENDS IN NEUROSCIENCES (2010)
HITS-CLIP: panoramic views of protein-RNA regulation in living cells
Robert B. Darnell
WILEY INTERDISCIPLINARY REVIEWS-RNA (2010)
Minocycline and neurodegenerative diseases
Hye-Sun Kim et al.
BEHAVIOURAL BRAIN RESEARCH (2009)
Making synaptic plasticity and memory last: mechanisms of translational regulation
Joel D. Richter et al.
GENES & DEVELOPMENT (2009)
Fragile X Mental Retardation Protein Regulates the Levels of Scaffold Proteins and Glutamate Receptors in Postsynaptic Densities
Janin Schuett et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Deregulation of EIF4E: a novel mechanism for autism
M. Neves-Pereira et al.
JOURNAL OF MEDICAL GENETICS (2009)
A pilot open label, single dose trial of fenobam in adults with fragile X syndrome
E. Berry-Kravis et al.
JOURNAL OF MEDICAL GENETICS (2009)
Altered Hippocampal Synaptic Plasticity in the Fmr1 Gene Family Knockout Mouse Models
Jing Zhang et al.
JOURNAL OF NEUROPHYSIOLOGY (2009)
Requirement for Protein Synthesis at Developing Synapses
Joseph Sebeo et al.
JOURNAL OF NEUROSCIENCE (2009)
The FXG: A Presynaptic Fragile X Granule Expressed in a Subset of Developing Brain Circuits
Sean B. Christie et al.
JOURNAL OF NEUROSCIENCE (2009)
The Fragile X Mental Retardation Protein in Circadian Rhythmicity and Memory Consolidation
Cheryl L. Gatto et al.
MOLECULAR NEUROBIOLOGY (2009)
Translational Control of Long-Lasting Synaptic Plasticity and Memory
Mauro Costa-Mattioli et al.
NEURON (2009)
Presynaptic translation: stepping out of the postsynaptic shadow
Michael R. Akins et al.
FRONTIERS IN NEURAL CIRCUITS (2009)
A Mouse Model of the Human Fragile X Syndrome I304N Mutation
Julie B. Zang et al.
PLOS GENETICS (2009)
Minocycline promotes dendritic spine maturation and improves behavioural performance in the fragile X mouse model
T. V. Bilousova et al.
JOURNAL OF MEDICAL GENETICS (2009)
The Autistic Neuron: Troubled Translation?
Raymond J. Kelleher et al.
CELL (2008)
The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP
Ilaria Napoli et al.
CELL (2008)
Imbalance of Neocortical Excitation and Inhibition and Altered UP States Reflect Network Hyperexcitability in the Mouse Model of Fragile X Syndrome
Jay R. Gibson et al.
JOURNAL OF NEUROPHYSIOLOGY (2008)
Homer interactions are necessary for metabotropic glutamate receptor-induced long-term depression and translational activation
Jennifer A. Ronesi et al.
JOURNAL OF NEUROSCIENCE (2008)
Loss of the Tuberous Sclerosis Complex Tumor Suppressors Triggers the Unfolded Protein Response to Regulate Insulin Signaling and Apoptosis
Umut Ozcan et al.
MOLECULAR CELL (2008)
Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila
Shuang Chang et al.
NATURE CHEMICAL BIOLOGY (2008)
Excess protein synthesis in Drosophila Fragile X mutants impairs long-term memory
Francois V. Bolduc et al.
NATURE NEUROSCIENCE (2008)
Altered protein synthesis is a trigger for long-term memory formation
Eric Klann et al.
NEUROBIOLOGY OF LEARNING AND MEMORY (2008)
Features of 80S mammalian ribosome and its subunits
Tatyana V. Budkevich et al.
NUCLEIC ACIDS RESEARCH (2008)
The Cyclic AMP Cascade Is Altered in the Fragile X Nervous System
Daniel J. Kelley et al.
PLOS ONE (2007)
Presynaptic Fmr1 genotype influences the degree of synaptic connectivity in a mosaic mouse model of fragile X syndrome
Jesse E. Hanson et al.
JOURNAL OF NEUROSCIENCE (2007)
Decreased expression of the GABAA receptor in fragile X syndrome
Charlotte D'Hulst et al.
BRAIN RESEARCH (2006)
Dynamic translational and proteasomal regulation of fragile X mental retardation protein controls mGluR-dependent long-term depression
Lingfei Hou et al.
NEURON (2006)
Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome
ED Nosyreva et al.
JOURNAL OF NEUROPHYSIOLOGY (2006)
Local functions for FMRP in axon growth cone motility and activity-dependent regulation of filopodia and spine synapses
Laura N. Antar et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2006)
SynGAP regulates synaptic strength and mitogen-activated protein kinases in cultured neurons
G Rumbaugh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Tuberous sclerosis: a GAP at the crossroads of multiple signaling pathways
DJ Kwiatkowski et al.
HUMAN MOLECULAR GENETICS (2005)
Rho GTPases, dendritic structure, and mental retardation
SE Newey et al.
JOURNAL OF NEUROBIOLOGY (2005)
Postadolescent changes in regional cerebral protein synthesis:: An in vivo study in the Fmr1 null mouse
M Qin et al.
JOURNAL OF NEUROSCIENCE (2005)
Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes
JC Darnell et al.
GENES & DEVELOPMENT (2005)
Decreased GABAA receptor expression in the seizure-prone fragile X mouse
A El Idrissi et al.
NEUROSCIENCE LETTERS (2005)
Pharmacological rescue of synaptic plasticity, courtship behavior, and mushroom body defects in a Drosophila model of fragile X syndrome
SMJ McBride et al.
NEURON (2005)
Biochemical evidence for the association of fragile X mental retardation protein with brain polyribosomal ribonucleoparticles
EW Khandjian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Fragile X mental retardation protein is associated with translating polyribosomes in neuronal cells
G Stefani et al.
JOURNAL OF NEUROSCIENCE (2004)
Biochemical mechanisms for translational regulation in synaptic plasticity
E Klann et al.
NATURE REVIEWS NEUROSCIENCE (2004)
Synaptic plasticity and translation initiation
E Klann et al.
LEARNING & MEMORY (2004)
The role of a clinically important mutation in the fold and RNA-binding properties of KH motifs
A Ramos et al.
RNA (2003)
The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at Synapses
F Zalfa et al.
CELL (2003)
Altered synaptic plasticity in a mouse model of fragile X mental retardation
KM Huber et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Reduced cortical synaptic plasticity and GluR1 expression associated with fragile X mental retardation protein deficiency
JX Li et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2002)
Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function
YQ Zhang et al.
CELL (2001)
The fragile X mental retardation protein inhibits translation via interacting with mRNA
ZZ Li et al.
NUCLEIC ACIDS RESEARCH (2001)
Evidence that fragile X mental retardation protein is a negative regulator of translation
B Laggerbauer et al.
HUMAN MOLECULAR GENETICS (2001)
Role for rapid dendritic protein synthesis in hippocampal mGluR-dependent long-term depression
KM Huber et al.
SCIENCE (2000)
Sequence-specific RNA binding by a Nova KH domain: Implications for paraneoplastic disease and the fragile X syndrome
HA Lewis et al.
CELL (2000)