4.7 Article

Differential coupling of visual cortex with default or frontal-parietal network based on goals

Journal

NATURE NEUROSCIENCE
Volume 14, Issue 7, Pages 830-832

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/nn.2823

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Funding

  1. US National Institutes of Health [5R01AG030395]
  2. Larry L. Hillblom Center for the Biology of Aging

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The relationship between top-down enhancement and suppression of sensory cortical activity and large-scale neural networks remains unclear. Functional connectivity analysis of human functional magnetic resonance imaging data revealed that visual cortical areas that selectively process relevant information are functionally connected with the frontal-parietal network, whereas those that process irrelevant information are simultaneously coupled with the default network. This indicates that sensory cortical regions are differentially and dynamically coupled with distinct networks on the basis of task goals.

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