Journal
NATURE NEUROSCIENCE
Volume 14, Issue 11, Pages 1413-1415Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nn.2915
Keywords
-
Categories
Funding
- Biotechnology and Biological Sciences Research Council
- Wellcome Trust (OXION Initiative)
- EPA Cephalosporin Fund
- BBSRC [BB/H002383/2] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/H002383/2] Funding Source: researchfish
- Medical Research Council [G1000183B, G0001354, G0001354B] Funding Source: researchfish
Ask authors/readers for more resources
Postsynaptic spines at CA3-CA1 synapses differ in glutamate receptor composition according to the hemispheric origin of CA3 afferents. To study the functional consequences of this asymmetry, we used optogenetic tools to selectively stimulate axons of CA3 pyramidal cells originating in either left or right mouse hippocampus. We found that left CA3 input produced more long-term potentiation at CA1 synapses than right CA3 input as a result of differential expression of GluN2B subunit-containing NMDA receptors.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
