Journal
NATURE NEUROSCIENCE
Volume 14, Issue 11, Pages 1416-1417Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nn.2919
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Funding
- National Institute of Mental Health [MH52090]
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A major controversy in the study of memory concerns whether there are distinct medial temporal lobe (MTL) substrates of recollection and familiarity. Studies using receiver operating characteristics analyses of recognition memory indicate that the hippocampus is essential for recollection, but not for familiarity. We found the converse pattern in the amygdala, wherein damage impaired familiarity while sparing recollection. Combined with previous findings, these results dissociate recollection and familiarity by selective MTL damage.
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