4.7 Article

Lateral prefrontal cortex and self-control in intertemporal choice

Journal

NATURE NEUROSCIENCE
Volume 13, Issue 5, Pages 538-539

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/nn.2516

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Funding

  1. Swiss National Science Foundation [PA001-15327, PBZH1-110268, PP00P1-123381]
  2. US National Science Foundation [SES-0720932, SES-0922743]

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Disruption of function of left, but not right, lateral prefrontal cortex (LPFC) with low-frequency repetitive transcranial magnetic stimulation (rTMS) increased choices of immediate rewards over larger delayed rewards. rTMS did not change choices involving only delayed rewards or valuation judgments of immediate and delayed rewards, providing causal evidence for a neural lateral-prefrontal cortex-based self-control mechanism in intertemporal choice.

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