Journal
NATURE NEUROSCIENCE
Volume 13, Issue 4, Pages 419-421Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nn.2510
Keywords
-
Categories
Funding
- National Institute on Drug Abuse [R01DA019670-04]
Ask authors/readers for more resources
Psychopathy is a personality disorder that is strongly linked to criminal behavior. Using [(18)F]fallypride positron emission tomography and blood oxygen level-dependent functional magnetic resonance imaging, we found that impulsive-antisocial psychopathic traits selectively predicted nucleus accumbens dopamine release and reward anticipation-related neural activity in response to pharmacological and monetary reinforcers, respectively. These findings suggest that neurochemical and neurophysiological hyper-reactivity of the dopaminergic reward system may comprise a neural substrate for impulsive-antisocial behavior and substance abuse in psychopathy.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available