Journal
NATURE NEUROSCIENCE
Volume 11, Issue 2, Pages 131-133Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nn2038
Keywords
-
Categories
Ask authors/readers for more resources
Pro- and mature BDNF activate very different receptors and intracellular pathways, potentially leading to either neuronal death or survival. Here we examined the biochemistry of endogenous BDNF in mouse neurons using sensitive reagents and found that pro-BDNF is rapidly converted intracellularly to mature BDNF, the latter being stored and released by excitatory input.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available