Journal
NATURE NANOTECHNOLOGY
Volume 4, Issue 7, Pages 411-414Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/NNANO.2009.175
Keywords
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Funding
- PHS HHS [HHSN261200800001E] Funding Source: Medline
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The pharmaceutical industry is developing increasing numbers of drugs and diagnostics based on nanoparticles, and evaluating the immune response to these diverse formulations has become a challenge for scientists and regulatory agencies alike. An international panel of scientists and representatives from various agencies and companies reviewed the limitations of current tests at a workshop held at the National Cancer Institute in Frederick, Maryland. This article outlines practical strategies for identifying and controlling interferences in common evaluation methods and the implications for regulation.
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