4.8 Article

Comprehensive analysis of DNA methylation data with RnBeads

Journal

NATURE METHODS
Volume 11, Issue 11, Pages 1138-1140

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/NMETH.3115

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Funding

  1. European Union [282510 (BLUEPRINT), 267038 (NOTOX)]
  2. German Science Ministry [01KU1216A (DEEP)]

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RnBeads is a software tool for large-scale analysis and interpretation of DNA methylation data, providing a user-friendly analysis workflow that yields detailed hypertext reports (http://rnbeads.mpi-inf.mpg.de/). Supported assays include whole-genome bisulfite sequencing, reduced representation bisulfite sequencing, Infinium microarrays and any other protocol that produces high-resolution DNA methylation data. Notable applications of RnBeads include the analysis of epigenome-wide association studies and epigenetic biomarker discovery in cancer cohorts.

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