Journal
NATURE METHODS
Volume 11, Issue 5, Pages 552-554Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/NMETH.2921
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Funding
- US National Institutes of Health [R01AIO66975, P01 GM0066275]
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We present a simple and general approach termed REsemble for quantifying population overlap and structural,similarity between ensembles. This approach captures improvements in the quality of ensembles determined using increasing input experimental data-improvements that go undetected when conventional methods for comparing ensembles are used-and reveals unexpected similarities between RNA ensembles determined using NMR and molecular dynamics simulations.
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