Journal
NATURE METHODS
Volume 11, Issue 2, Pages 141-147Publisher
NATURE PORTFOLIO
DOI: 10.1038/NMETH.2805
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Funding
- US National Science Foundation [CBET-1037097, ECCS-1045621, CBET-1158638, ECCS-1101947, CBET-1264356]
- US National Institutes of Health [P41EB015903]
- Directorate For Engineering [1037097, 1101947] Funding Source: National Science Foundation
- Directorate For Engineering
- Div Of Chem, Bioeng, Env, & Transp Sys [1264356, 1158638] Funding Source: National Science Foundation
- Div Of Chem, Bioeng, Env, & Transp Sys [1037097] Funding Source: National Science Foundation
- Div Of Electrical, Commun & Cyber Sys [1101947] Funding Source: National Science Foundation
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Optofluidic biolasers are emerging as a highly sensitive way to measure changes in biological molecules. Biolasers, which incorporate biological material into the gain medium and contain an optical cavity in a fluidic environment, can use the amplification that occurs during laser generation to quantify tiny changes in biological processes in the gain medium. We describe the principle of the optofluidic biolaser, review recent progress and provide our outlooks on potential applications and directions for developing this technology.
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