Journal
NATURE METHODS
Volume 8, Issue 10, Pages 829-U89Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/NMETH.1706
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Funding
- California Institute for Regenerative Medicine [TB1-01186]
- O'Keefe Foundation
- Millipore Foundation
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For some highly endangered species there are too few reproductively capable animals to maintain adequate genetic diversity, and extraordinary measures are necessary to prevent extinction. We report generation of induced pluripotent stem cells (iPSCs) from two endangered species: a primate, the drill, Mandrillus leucophaeus and the nearly extinct northern white rhinoceros, Ceratotherium simum cottoni. iPSCs may eventually facilitate reintroduction of genetic material into breeding populations.
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