Journal
NATURE METHODS
Volume 8, Issue 9, Pages 731-736Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nmeth.1671
Keywords
-
Categories
Funding
- US National Institutes of Health [HL060435]
- Swiss National Science Foundation [PBELP3-127902]
- Rotary Ambassadorial Scholarship
- Medicus Exchange Scholarship
- Marie Curie-Reintegration grant [FP7-People-2007-4-3-IRG, 230929]
- Massachusetts Institute of Technology-Portugal
- Portuguese Foundation for Science and Technology [PTDC/SAU-BEB/098468/2008, PTDC/CTM/099659/2008]
- Fundação para a Ciência e a Tecnologia [PTDC/SAU-BEB/098468/2008] Funding Source: FCT
- Swiss National Science Foundation (SNF) [PBELP3-127902] Funding Source: Swiss National Science Foundation (SNF)
Ask authors/readers for more resources
The self-renewal and differentiation of human pluripotent stem cells (hPSCs) have typically been studied in flat, two-dimensional (2D) environments. In this Perspective, we argue that 3D model systems may be needed in addition, as they mimic the natural 3D tissue organization more closely. We survey methods that have used 3D biomaterials for expansion of undifferentiated hPSCs, directed differentiation of hPSCs and transplantation of differentiated hPSCs in vivo.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
