4.8 Article

Near-infrared fluorescent proteins

Journal

NATURE METHODS
Volume 7, Issue 10, Pages 827-U1520

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/NMETH.1501

Keywords

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Funding

  1. Russian Academy of Sciences
  2. Howard Hughes Medical Institute [55005618]
  3. US National Institutes of Health [R01CA136553, R01CA136829, P50CA093990]
  4. Rosnauka [02.512.12.2053]
  5. Russian Foundation for Basic Research [08-04-01702-a, 10-04-01042]

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Fluorescent proteins with emission wavelengths in the near-infrared and infrared range are in high demand for whole-body imaging techniques. Here we report near-infrared dimeric fluorescent proteins eqFP650 and eqFP670. To our knowledge, eqFP650 is the brightest fluorescent protein with emission maximum above 635 nm, and eqFP670 displays the most red-shifted emission maximum and high photostability.

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