Journal
NATURE METHODS
Volume 7, Issue 3, Pages S42-S55Publisher
NATURE PORTFOLIO
DOI: 10.1038/NMETH.1427
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Funding
- European Union [LSHC-CT-2007-037472]
- Klaus Tschira Foundation
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Structural biology is rapidly accumulating a wealth of detailed information about protein function, binding sites, RNA, large assemblies and molecular motions. These data are increasingly of interest to a broader community of life scientists, not just structural experts. Visualization is a primary means for accessing and using these data, yet visualization is also a stumbling block that prevents many life scientists from benefiting from three-dimensional structural data. In this review, we focus on key biological questions where visualizing three-dimensional structures can provide insight and describe available methods and tools.
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