Journal
NATURE METHODS
Volume 5, Issue 7, Pages 605-607Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nmeth.1220
Keywords
-
Categories
Funding
- NIAID NIH HHS [P01 AI053194, P01 AI053194-07] Funding Source: Medline
Ask authors/readers for more resources
Live imaging of the actin cytoskeleton is crucial for the study of many fundamental biological processes, but current approaches to visualize actin have several limitations. Here we describe Lifeact, a 17-amino-acid peptide, which stained filamentous actin (F-actin) structures in eukaryotic cells and tissues. Lifeact did not interfere with actin dynamics in vitro and in vivo and in its chemically modified peptide form allowed visualization of actin dynamics in nontransfectable cells.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available