Journal
NATURE MEDICINE
Volume 19, Issue 1, Pages 22-24Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nm.3053
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Production of the amyloid-beta peptide in Alzheimer's disease by the gamma-secretase complex can be regulated by certain G protein-coupled receptors. This regulation seems to be mediated by beta-arrestin-2, whose expression was found to be elevated in Alzheimer's disease brains (pages 43-49).
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