Journal
NATURE MEDICINE
Volume 19, Issue 9, Pages 1092-1094Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nm.3333
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Funding
- Cancer Research UK [14355, 12888] Funding Source: researchfish
- Cancer Research UK [14355, 12888] Funding Source: Medline
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Interleukin-17 (IL-17) released in the tumor microenvironment in response to drugs blocking vascular endothelial growth factor (VEGF) triggers stromal-derived inflammatory and VEGF-independent angiogenic programs that induce the drug refractoriness found in cancers resistant to anti-angiogenic therapy (pages 1114-1123).
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