4.8 Editorial Material

FOXO3a and β-catenin co-localization: double trouble in colon cancer?

Journal

NATURE MEDICINE
Volume 18, Issue 6, Pages 854-856

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/nm.2799

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Metastatic colorectal cancer is a largely incurable disease with a pressing need for targeted therapies. A new study sheds light on a surprising interaction between FOXO3a and beta-catenin in metastatic colorectal cancer, suggesting new therapeutic avenues for agents targeting the PI3K-AKT pathway (pages 892-901).

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