Related references
Note: Only part of the references are listed.HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment
Britta Weigelt et al.
BREAST CANCER RESEARCH AND TREATMENT (2010)
Zoledronic acid impairs myeloid differentiation to tumour-associated macrophages in mesothelioma
J. D. Veltman et al.
BRITISH JOURNAL OF CANCER (2010)
Reprogramming Human Cancer Cells in the Mouse Mammary Gland
Karen M. Bussard et al.
CANCER RESEARCH (2010)
MK-2461, a Novel Multitargeted Kinase Inhibitor, Preferentially Inhibits the Activated c-Met Receptor
Bo-Sheng Pan et al.
CANCER RESEARCH (2010)
Macrophage Diversity Enhances Tumor Progression and Metastasis
Bin-Zhi Qian et al.
CELL (2010)
Oxidative stress promotes myofibroblast differentiation and tumour spreading
Aurore Toullec et al.
EMBO MOLECULAR MEDICINE (2010)
Raf-induced MMP9 disrupts tissue architecture of human breast cells in three-dimensional culture and is necessary for tumor growth in vivo
Alain Beliveau et al.
GENES & DEVELOPMENT (2010)
Cancer and Inflammation: Promise for Biologic Therapy
Sandra Demaria et al.
JOURNAL OF IMMUNOTHERAPY (2010)
Enzymatic Depletion of Tumor Hyaluronan Induces Antitumor Responses in Preclinical Animal Models
Curtis B. Thompson et al.
MOLECULAR CANCER THERAPEUTICS (2010)
Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anticancer drug activity
Douglas W. McMillin et al.
NATURE MEDICINE (2010)
Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment
Vivian Barry-Hamilton et al.
NATURE MEDICINE (2010)
Responsiveness to PI3K and MEK Inhibitors in Breast Cancer. Use of a 3D Culture System to Study Pathways Related to Hormone Independence in Mice
Maria Laura Polo et al.
PLOS ONE (2010)
Stromal genes discriminate preinvasive from invasive disease, predict outcome, and highlight inflammatory pathways in digestive cancers
Amel Saadi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein-α
Matthew Kraman et al.
SCIENCE (2010)
Stromal Cell Expression of Caveolin-1 Predicts Outcome in Breast Cancer
Erica K. Sloan et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
Prognostic Significance of Stromal Platelet-Derived Growth Factor β-Receptor Expression in Human Breast Cancer
Janna Paulsson et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
An Absence of Stromal Caveolin-1 Expression Predicts Early Tumor Recurrence and Poor Clinical Outcome in Human Breast Cancers
Agnieszka K. Witkiewicz et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
Integrins during evolution: Evolutionary trees and model organisms
Mark S. Johnson et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)
Endothelial Cell Migration and Vascular Endothelial Growth Factor Expression Are the Result of Loss of Breast Tissue Polarity
Amy Chen et al.
CANCER RESEARCH (2009)
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
Kandice R. Levental et al.
CELL (2009)
Sustained activation of STAT5 is essential for chromatin remodeling and maintenance of mammary-specific function
Ren Xu et al.
JOURNAL OF CELL BIOLOGY (2009)
CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers
J. A. Burger et al.
LEUKEMIA (2009)
A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer
Pierre Farmer et al.
NATURE MEDICINE (2009)
Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer
Kenneth P. Olive et al.
SCIENCE (2009)
Microenvironmental regulation of metastasis
Johanna A. Joyce et al.
NATURE REVIEWS CANCER (2009)
β1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts
Catherine C. Park et al.
CANCER RESEARCH (2008)
A human breast cell model of preinvasive to invasive transition
Aylin Rizki et al.
CANCER RESEARCH (2008)
Macrophages define the invasive microenvironment in breast cancer
Jeffrey W. Pollard
JOURNAL OF LEUKOCYTE BIOLOGY (2008)
Stromal gene expression predicts clinical outcome in breast cancer
Greg Finak et al.
NATURE MEDICINE (2008)
The tumor microenvironment and its role in promoting tumor growth
T. L. Whiteside
ONCOGENE (2008)
MMPs as therapeutic targets - Still a viable option?
Barbara Fingleton
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2008)
Cysteine cathepsin proteases as pharmacological targets in cancer
Carmela Palermo et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2008)
Inhibition of cysteine cathepsin protease activity enhances chemotherapy regimens by decreasing tumor growth and invasiveness in a mouse model of multistage cancer
Katherine M. Bell-McGuinn et al.
CANCER RESEARCH (2007)
Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets
Teru Hideshima et al.
NATURE REVIEWS CANCER (2007)
Morphogens, morphostats, microarchitecture and malignancy
John D. Potter
NATURE REVIEWS CANCER (2007)
Targeting the tumor microenvironment
Paraic A. Kenny et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2007)
On the frequency of occurrence of occult carcinoma of the prostrate
Arnold Rice Rich
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2007)
Mammographic density and the risk and detection of breast cancer
Norman F. Boyd et al.
NEW ENGLAND JOURNAL OF MEDICINE (2007)
Achievements in systemic therapies in the pregenomic era in metastatic breast cancer
Mariantonietta Colozza et al.
ONCOLOGIST (2007)
Reprogramming metastatic tumour cells with embryonic microenvironments
Mary J. C. Hendrix et al.
NATURE REVIEWS CANCER (2007)
Stromal and epithelial caveolin-1 both confer a protective effect against mammary hyperplasia and tumorigenesis: Caveolin-1 antagonizes cyclin D1 function in mammary epithelial cells
Terence M. Williams et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
A three-dimensional model to study the epigenetic effects induced by the microenvironment of human embryonic stem cells
Lynne-Marie Postovit et al.
STEM CELLS (2006)
β1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo
CC Park et al.
CANCER RESEARCH (2006)
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
RN Kaplan et al.
NATURE (2005)
Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability
DC Radisky et al.
NATURE (2005)
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
A Orimo et al.
CELL (2005)
Incidental lung cancers identified at coronial autopsy: implications for overdiagnosis of lung cancer by screening
RL Manser et al.
RESPIRATORY MEDICINE (2005)
Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival
HY Chang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Proteasome inhibition as a novel therapeutic target in human cancer
SV Rajkumar et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
N Ferrara et al.
NATURE REVIEWS DRUG DISCOVERY (2004)
TGF-β signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia
NA Bhowmick et al.
SCIENCE (2004)
Gene expression signature of fibroblast serum response predicts human cancer progression: Similarities between tumors and wounds
HY Chang et al.
PLOS BIOLOGY (2004)
In situ analyses of genome instability in breast cancer
K Chin et al.
NATURE GENETICS (2004)
Reprogramming of a melanoma genome by nuclear transplantation
K Hochedlinger et al.
GENES & DEVELOPMENT (2004)
The molecular triad OPG/RANK/RANKL: involvement in the orchestration of pathophysiological bone remodeling
S Theoleyre et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2004)
Stromal fibroblasts in cancer initiation and progression
NA Bhowmick et al.
NATURE (2004)
Friends or foes - Bipolar effects of the tumour stroma in cancer
MM Mueller et al.
NATURE REVIEWS CANCER (2004)
Insulin-like growth factor I induces migration and invasion of human multiple myeloma cells
YW Qiang et al.
BLOOD (2004)
Disruption of 3D tissue integrity facilitates adenovirus infection by deregulating the coxsackievirus and adenovirus receptor
M Anders et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Role of angiogenesis in tumor growth and metastasis
J Folkman
SEMINARS IN ONCOLOGY (2002)
Phenotypic reversion or death of cancer cells by altering signaling pathways in three-dimensional contexts
F Wang et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2002)
β4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium
VM Weaver et al.
CANCER CELL (2002)
Senescent fibroblasts promote epithelial cell growth and tumorigenesis: A link between cancer and aging
A Krtolica et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini
SK Muthuswamy et al.
NATURE CELL BIOLOGY (2001)
Share Paper
