Journal
NATURE MEDICINE
Volume 17, Issue 3, Pages 313-319Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nm.2304
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Over the last decade, the notion that tumors are maintained by their own stem cells, the so-called cancer stem cells, has created great excitement in the research community. This review attempts to summarize the underlying concepts of this notion, to distinguish hard facts from beliefs and to define the future challenges of the field.
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