Journal
NATURE MEDICINE
Volume 16, Issue 5, Pages 517-518Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nm0510-517
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Funding
- NCI NIH HHS [R01 CA064140] Funding Source: Medline
- NATIONAL CANCER INSTITUTE [R01CA064140] Funding Source: NIH RePORTER
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Mammalian genomes harbor regulatory elements from ancient retroviral infections. These retroviral remnants are normally silenced by DNA methylation-but this can change. Reactivation of one such element triggers the expression of a nearby oncogene during the development of Hodgkin's lymphoma (571-579).
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