Journal
NATURE MEDICINE
Volume 16, Issue 8, Pages 851-852Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nm0810-851
Keywords
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Funding
- NHLBI NIH HHS [R01 HL042846, R01 HL098542, P01 HL031950] Funding Source: Medline
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Blood coagulation protects from microbial infections. A recent study now shows that neutrophils fine tune the procoagulant response to invading pathogens (pages 887-896). Neutrophils degrade an inhibitor of coagulation, locally 'trapping' bacteria in small blood vessels. But they also increase blood clots in large vessels in the absence of infection, which may be relevant for the treatment of thrombosis.
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