Journal
NATURE MEDICINE
Volume 15, Issue 11, Pages 1245-1246Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nm1109-1245
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Injection of activated protein C (APC) is the last resort to rescue a patient with severe sepsis. Research into how APC works reveals that the drug inactivates histones (pages 1318-1321), which are toxic during severe sepsis.
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