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Serine-threonine kinases in TCR signaling

Journal

NATURE IMMUNOLOGY
Volume 15, Issue 9, Pages 808-814

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/ni.2941

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Funding

  1. Wellcome Trust [097418] Funding Source: Medline

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T lymphocyte proliferation and differentiation are controlled by signaling pathways initiated by the T cell antigen receptor. Here we explore how key serine-threonine kinases and their substrates mediate T cell signaling and coordinate T cell metabolism to meet the metabolic demands of participating in an immune response.

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