Related references
Note: Only part of the references are listed.Antagonistic interplay between ThPOK and Runx in lineage choice of thymocytes
Takeshi Egawa et al.
BLOOD CELLS MOLECULES AND DISEASES (2009)
IL7-hCD25 and IL7-Cre BAC Transgenic Mouse Lines: New Tools for Analysis of IL-7 Expressing Cells
John F. Repass et al.
GENESIS (2009)
Loss of STAT5 causes liver fibrosis and cancer development through increased TGF-β and STAT3 activation
Atsushi Hosui et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
CD4-CD8 Lineage Differentiation: Thpok-ing into the Nucleus
Lie Wang et al.
JOURNAL OF IMMUNOLOGY (2009)
Characterization of the thymic IL-7 niche in vivo
Nuno L. Alves et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
CD4-CD8 lineage commitment is regulated by a silencer element at the ThPOK transcription-factor locus
Xi He et al.
IMMUNITY (2008)
Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate
Sawako Muroi et al.
NATURE IMMUNOLOGY (2008)
ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage
Takeshi Egawa et al.
NATURE IMMUNOLOGY (2008)
Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4+ T cells
Lie Wang et al.
NATURE IMMUNOLOGY (2008)
Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development
Ruka Setoguchi et al.
SCIENCE (2008)
Lineage fate and intense debate: myths, models and mechanisms of CD4-versus CD8-lineage choice
Alfred Singer et al.
NATURE REVIEWS IMMUNOLOGY (2008)
Acquisition of a functional T cell receptor during T lymphocyte development is enforced by HEB and E2A transcription factors
Mary Elizabeth Jones et al.
IMMUNITY (2007)
'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR
Jung-Hyun Park et al.
NATURE IMMUNOLOGY (2007)
The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells
Takeshi Egawa et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Cytokine signal transduction is suppressed in preselection double-positive thymocytes and restored by positive selection
Q Yu et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection
GP Sun et al.
NATURE IMMUNOLOGY (2005)
Dual functions of Runx proteins for reactivating CD8 and silencing CD4 at the commitment process into CD8 thymocytes
T Sato et al.
IMMUNITY (2005)
The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment
X He et al.
NATURE (2005)
Ontogeny and regulation of IL-7-expressing thymic epithelial cells
M Zamisch et al.
JOURNAL OF IMMUNOLOGY (2005)
Thymocytes between the β-selection and positive selection checkpoints are nonresponsive to IL-7 as assessed by STAT-5 phosphorylation
CJV Van de Wiele et al.
JOURNAL OF IMMUNOLOGY (2004)
CCR7 directs the migration of thymocytes into the thymic medulla
J Kwan et al.
JOURNAL OF IMMUNOLOGY (2004)
IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and RORγt:: Impact on thymocyte development
Q Yu et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation
Y Cui et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
CCR7 signals are essential for cortex-medulla migration of developing thymocytes
T Ueno et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Centromeric repositioning of coreceptor loci predicts their stable silencing and the CD4/CD8 lineage choice
M Merkenschlager et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Unraveling a revealing paradox:: Why major histocompatibility complex I-signaled thymocytes Paradoxically appear as CD4+8lo transitional cells during positive selection of CD8+ T cells
R Bosselut et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Suppressor of cytokine signaling-1 is a critical regulator of interleukin-7-dependent CD8+ T cell differentiation
MMW Chong et al.
IMMUNITY (2003)
In vitro evidence that cytokine receptor signals are required for differentiation of double positive thymocytes into functionally mature CD8+ T cells
Q Yu et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Suppressors of cytokine signaling and immunity
M Kubo et al.
NATURE IMMUNOLOGY (2003)
Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development
I Taniuchi et al.
CELL (2002)
New perspectives on a developmental dilemma: the kinetic signalling model and the importance of signal duration for the CD4/CD8 lineage decision
A Singer
CURRENT OPINION IN IMMUNOLOGY (2002)
A mutant form of JAB/SOCS1 augments the cytokine-induced JAK/STAT pathway by accelerating degradation of wild-type JAB/CIS family proteins through the SOCS-box
T Hanada et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Transient inhibition of interleukin 4 signaling by T cell receptor ligation
JF Zhu et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Coreceptor reversal in the thymus:: Signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells
E Brugnera et al.
IMMUNITY (2000)
Share Paper
