4.7 Editorial Material

Basophils trump dendritic cells as APCs for TH2 responses

Journal

NATURE IMMUNOLOGY
Volume 10, Issue 7, Pages 679-681

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/ni0709-679

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Funding

  1. Intramural NIH HHS [Z01 AI001019-01] Funding Source: Medline

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Dendritic cells are best known as antigen-presenting cells that initiate adaptive immune responses. Three new papers suggest that basophils initiate allergen-and helminth-driven CD4(+) T helper type 2 responses by functioning as antigen-presenting cells in draining lymph nodes.

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