4.7 Editorial Material

Regulation of NKG2D ligands: a purposeful but delicate affair

Journal

NATURE IMMUNOLOGY
Volume 9, Issue 9, Pages 1013-1015

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NATURE PUBLISHING GROUP
DOI: 10.1038/ni0908-1013

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New findings show that cellular microRNAs 'calibrate' the baseline expression of mRNAs encoding stress-inducible ligands of the activating NKG2D receptor. This regulation serves to protect innocent cells but may be exploited by tumors and viruses to thwart immune attack.

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