Journal
NATURE IMMUNOLOGY
Volume 9, Issue 6, Pages 583-584Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ni0608-583
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The T cell receptor (TCR) is functionally coupled to a constellation of ten immunoreceptor tyrosine-based activation motifs (ITAMs). A new study suggests that this large number of ITAMs is mandatory for preventing autoimmunity.
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