Journal
NATURE GENETICS
Volume 42, Issue 4, Pages 292-294Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ng.553
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Funding
- BMBF through the National Genome Research Network (NGFN)
- PopGen Biobank
- Cooperative Research in the Region of Augsburg (KORA)
- German Federal Ministry of Education, Science, Research and Technology
- State of Bavaria
- Munich Center of Health Sciences (MC Health)
- UK Medical Research Council [G0000934]
- Wellcome Trust [068545/Z/02]
- MRC [G0000934, MC_qA137934] Funding Source: UKRI
- Medical Research Council [MC_qA137934, G0000934] Funding Source: researchfish
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We performed a genome-wide association analysis of 1,897,764 SNPs in 1,043 German ulcerative colitis (UC) cases and 1,703 controls. We discovered new associations at chromosome 7q22 (rs7809799) and at chromosome 22q13 in IL17REL (rs5771069) and confirmed these associations in six replication panels (2,539 UC cases and 5,428 controls) from different regions of Europe (overall study sample P(rs7809799) = 8.81 x 10(-11) and P(rs5771069) = 4.21 x 10(-8), respectively).
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