Journal
NATURE GENETICS
Volume 42, Issue 10, Pages 830-831Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ng.651
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Funding
- Direct For Social, Behav & Economic Scie [0813715] Funding Source: National Science Foundation
- Division Of Behavioral and Cognitive Sci [0813715] Funding Source: National Science Foundation
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The ratio of X-linked to autosomal diversity was estimated from an analysis of six human genome sequences and found to deviate from the expected value of 0.75. However, the direction of this deviation depends on whether a particular sequence is close to or far from the nearest gene. This pattern may be explained by stronger locally acting selection on X-linked genes compared with autosomal genes, combined with larger effective population sizes for females than for males.
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