Journal
NATURE GENETICS
Volume 41, Issue 10, Pages 1055-1057Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ng.444
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Funding
- NCI
- National Institutes of Health (NIH) [HHSN261200800001E]
- [CA129684]
- [CA131338]
- MRC [G0501019] Funding Source: UKRI
- Medical Research Council [G0501019] Funding Source: researchfish
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We report a genome-wide association study in 10,286 cases and 9,135 controls of European ancestry in the Cancer Genetic Markers of Susceptibility (CGEMS) initiative. We identify a new association with prostate cancer risk on chromosome 8q24 (rs620861, P = 1.3 x 10(-10), heterozygote OR = 1.17, 95% CI 1.10-1.24; homozygote OR = 1.33, 95% CI 1.21-1.45). This defines a new locus associated with prostate cancer susceptibility on 8q24.
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