Journal
NATURE GENETICS
Volume 40, Issue 9, Pages 1056-1058Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ng.209
Keywords
-
Categories
Funding
- US National Institute of Mental Health [MH062137, MH067288, MH063445, MH63420, N01MH80001]
- Johnson & Johnson Pharmaceutical Research & Development, Sylvan C. Herman Foundation, Stanley Medical Research Institute, Dauten Family, Merck Genome Research Institute
- National Health Medical Research Council
- National Center for Research Resources [U54 RR020278]
- MDF - The Bipolar Organization
- Neuroscience Research Charitable Trust
- central London NHS Blood Transfusion Service
- Priory Hospitals
- UK MRC [G9623693N, G0500791]
- Health Research Board and Science Foundation Ireland
- Trinity College Biobank
- Wellcome Trust, London
- Chief Scientist Office of the Scottish Executive
- MRC, London
- Medical Research Council [G9309834, G0701003, G0500791] Funding Source: researchfish
- MRC [G9309834, G0701003, G0500791] Funding Source: UKRI
Ask authors/readers for more resources
To identify susceptibility loci for bipolar disorder, we tested 1.8 million variants in 4,387 cases and 6,209 controls and identified a region of strong association (rs10994336, P = 9.1 x 10(-9)) in ANK3 (ankyrin G). We also found further support for the previously reported CACNA1C (alpha 1C subunit of the L-type voltage-gated calcium channel; combined P = 7.0 x 10(-8), rs1006737). Our results suggest that ion channelopathies may be involved in the pathogenesis of bipolar disorder.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
