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CROSS COUPLING When is free really free?

Journal

NATURE CHEMISTRY
Volume 2, Issue 12, Pages 1007-1009

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/nchem.913

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An organocatalytic method for constructing biaryls joins an increasing number of articles reporting metal-free analogues to reactions that traditionally have required a transition-metal catalyst. What does it take to prove that metal is not involved, and does it really matter?

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