Journal
NATURE CHEMICAL BIOLOGY
Volume 8, Issue 7, Pages 609-611Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/NCHEMBIO.960
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Funding
- US National Science Foundation [DBI-0606595]
- United States-Israel Binational Agricultural Research and Development Fund [IS-4234-09]
- US Department of Agriculture Cooperative State Research, Education and Extension Service [2011-04197]
- Danish Council for Strategic Research [10-093465]
- US National Institutes of Health [T32 GM008500]
- Div Of Biological Infrastructure
- Direct For Biological Sciences [0922805] Funding Source: National Science Foundation
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A hydrophobic cuticle consisting of waxes and the polyester cutin covers the aerial epidermis of all land plants, providing essential protection from desiccation and other stresses. We have determined the enzymatic basis of cutin polymerization through characterization of a tomato extracellular acyltransferase, CD1, and its substrate, 2-mono(10,16-dihydroxyhexadecanoyl)glycerol. CD1 has in vitro polyester synthesis activity and is required for cutin accumulation in vivo, indicating that it is a cutin synthase.
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