Related references
Note: Only part of the references are listed.The p53 circuit board
Kelly D. Sullivan et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2012)
A DR4:tBID axis drives the p53 apoptotic response by promoting oligomerization of poised BAX
Ryan E. Henry et al.
EMBO JOURNAL (2012)
NEMO and RIP1 Control Cell Fate in Response to Extensive DNA Damage via TNF-α Feedforward Signaling
Sharon Biton et al.
CELL (2011)
Nuclear initiated NF-kappa B signaling: NEMO and ATM take center stage
Shigeki Miyamoto
CELL RESEARCH (2011)
Targeting Anaplastic Lymphoma Kinase in Lung Cancer
Alice T. Shaw et al.
CLINICAL CANCER RESEARCH (2011)
Wild-type p53 controls cell motility and invasion by dual regulation of MET expression
Chang-Il Hwang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Signals from the Nucleus: Activation of NF-κB by Cytosolic ATM in the DNA Damage Response
Kamyar Hadian et al.
SCIENCE SIGNALING (2011)
The p53 Pathway as a Target in Cancer Therapeutics: Obstacles and Promise
Anna Mandinova et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method
Ting-Chao Chou
CANCER RESEARCH (2010)
MET signalling: principles and functions in development, organ regeneration and cancer
Livio Trusolino et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Anaplastic Lymphoma Kinase Inhibition in Non-Small-Cell Lung Cancer
Eunice L. Kwak et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Blinded by the Light: The Growing Complexity of p53
Karen H. Vousden et al.
CELL (2009)
The combined status of ATM and p53 link tumor development with therapeutic response
Hai Jiang et al.
GENES & DEVELOPMENT (2009)
PUMA Promotes Bax Translocation by Both Directly Interacting with Bax and by Competitive Binding to Bcl-X-L during UV-induced Apoptosis
Yingjie Zhang et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
Pharmacologic p53 Activation Blocks Cell Cycle Progression but Fails to Induce Senescence in Epithelial Cancer Cells
Baoying Huang et al.
MOLECULAR CANCER RESEARCH (2009)
Spheroid-based drug screen: considerations and practical approach
Juergen Friedrich et al.
NATURE PROTOCOLS (2009)
Awakening guardian angels: drugging the p53 pathway
Christopher J. Brown et al.
NATURE REVIEWS CANCER (2009)
Multiple p53-independent gene silencing mechanisms define the cellular response to p53 activation
Ramiro Paris et al.
CELL CYCLE (2008)
Pharmacokinetic-pharmacodynamic modeling of biomarker response and tumor growth inhibition to an orally available cMet kinase inhibitor in human tumor xenograft mouse models
Shinji Yamazaki et al.
DRUG METABOLISM AND DISPOSITION (2008)
Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer
Martin F. Lavin
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
Manabu Soda et al.
NATURE (2007)
Restoration of p53 function leads to tumour regression in vivo
Andrea Ventura et al.
NATURE (2007)
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
Wen Xue et al.
NATURE (2007)
p53-based cancer therapies: is defective p53 the Achilles heel of the tumor?
Aime A. Levesque et al.
CARCINOGENESIS (2007)
An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors
TR Brummelkamp et al.
NATURE CHEMICAL BIOLOGY (2006)
Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: Implications for therapy
C Tovar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Emerging cancer therapeutic opportunities target DNA-repair systems
Jian Ding et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2006)
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
LT Vassilev et al.
SCIENCE (2004)
Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM
I Hickson et al.
CANCER RESEARCH (2004)
Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors
N Issaeva et al.
NATURE MEDICINE (2004)
The role of gast in in colorectal carcinogenesis
AS Takhar et al.
SURGEON-JOURNAL OF THE ROYAL COLLEGES OF SURGEONS OF EDINBURGH AND IRELAND (2004)
Live or let die: The cell's response to p53
KH Vousden et al.
NATURE REVIEWS CANCER (2002)
Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound
VJN Bykov et al.
NATURE MEDICINE (2002)
Frequent allelic imbalance at the ATM locus in DNA multiploid colorectal carcinomas
T Sugai et al.
ONCOGENE (2001)
PUMA induces the rapid apoptosis of colorectal cancer cells
J Yu et al.
MOLECULAR CELL (2001)
PUMA, a novel proapoptotic gene, is induced by p53
K Nakano et al.
MOLECULAR CELL (2001)
Share Paper
